The generation of induced pluripotent stem cells (iPSCs) from differentiated somatic cells by Yamanaka factors, including pioneer transcription factors (TFs), has greatly reshaped Fresh Organic Vegetables our traditional understanding of cell plasticity and demonstrated the remarkable potential of pioneer TFs.In addition to iPSC reprogramming, pion
With the aggravation VITAMIN K/A/D3 LIQUID of social aging and the increase in work intensity, the prevalence of spinal degenerative diseases caused by intervertebral disc degeneration(IDD)has increased yearly, which has driven a heavy economic burden on patients and society.It is well known that IDD is associated with cell damage and degradation o
Phenotypic screening is an ideal strategy for the discovery of novel bioactive molecules.Using a customized high-throughput screening (HTS) assay employing primary T lymphocytes, we screened a small library of 4,398 compounds with unknown biological function/target to identify compounds eliciting immunomodulatory properties and discovered a sulfony